The Holy Jesus Hospital is a working office Newcastle upon Tyne, England, in the care of the National Trust. It is a Grade II* listed building.
The site of the hospital has been in use for 700 years helping the townspeople. There was an Augustinian friary on the site from the thirteenth century, then an almshouse for housing retired freemen, then a soup kitchen was built next to Almshouse in the nineteenth century, before the site acquired its current function as a working office. The building also serves as the basis of the Inner City Project of the National Trust. This project takes people of ages 12–25 and over 50 out to the countryside in order to increase appreciation of the city’s natural surroundings.
The building is of architectural interest because it still retains architectural elements from many previous centuries, including a 14th-century sacristy wall and 16th-century tower connected with the King’s Council of the North. It is also one of only two intact 17th-century brick buildings that survive in the city, the other being Alderman Fenwick’s House.